GRK 2154 - Materials for Brain

Within the GRK 2154, physicians are given the opportunity to intensively work on RTG-related scientific research tasks. Physicians are partially exempted from clinical tasks and are provided with protected research time to support the completion of their habilitation.

Dr. med. Jawid Madjidyar

Intracranial Aneurysm Wall Imaging in 3T MRI

Recent studies have suggested that wall enhancement of unruptured intracranial aneurysms in high-resolution MR imaging might serve as an imaging biomarker for higher risk of rupture. Histologic studies have revealed a possible association among inflammatory processes, degeneration, and destabilization of the aneurysm wall preceding rupture. Understanding the histologic condition underlying aneurysm wall enhancement could be an important step toward assessing the value of this method for risk stratification.

1. Development of a MRI-protocol for aneurysm wall characterization.
2. Correlation between MRI-findings and histopathological findings in operated aneurysms.
3. Longitudinal aneurysm wall imaging in patients with incidental aneurysms.