Research Training Group 2154 - Materials for Brain

  • 27.11.2020: Nacht der Wissenschaft
    On 27.11.2020, the "Rent-a-Scientist" program was offered as part of the “Nacht der Wissenschaft” (Night of Science). School classes were able to rent a scientist who would come to the school class and give a lesson in his or her research topic. Three members of the RTG 2154 were invited to schools in the Kiel region:
    Prof. Franz Faupel was invited to the Freie Waldorfschule Eckernförde and gave two teaching hours on the topic "How nanotechnology is changing our lives". Since several classes from the senior grades participated, a bigger venue was required. To fulfill the corona-related hygiene rules, the event took place in the sports hall. After an introduction to nanotechnology, the topics of nanoparticles, nanocomposites and nanocoatings were presented in more detail including biological and medical aspects as well as research projects of Prof. Faupel’s working group. Potential risks of nanomaterials were also addressed. The students and teachers enjoyed this interesting lesson, and at the end there was a lively discussion with many questions from the audience.
    The Probstei Community School in Schönberg invited two of our PhD students, Igor Barg and Torge Hartig, who held two teaching hours in a 12th grade class. They gave a lecture in front of 29 school students, entitled "Implants for the brain - the future of medicine". The students learned the basics of materials science and the anatomy and pathology of aneurysm, glioblastoma and epilepsy, the research topics of the RTG 2154. Igor and Torge presented the latest scientific approaches and methods for the production of implants for the treatment of these diseases. Due to Corona, unfortunately no experiments could be performed on site. However, the PhD students had prepared video clips in which they were able to show and explain the experiments they carry out in the laboratory. The lecture of Igor and Torge also received very positive feedback, and the students and teacher enjoyed the insights into Igor’s and Torge’s research!
    We are looking forward to the “Nacht der Wissenschaft” in 2021, and again renting out some scientists of the RTG 2154 to schools in the Kiel region.
    igba_toha
     
  • 07.11.2020: Unizeit article on the MOIN CC-PLUS Team

    In the November issue of the CAU Unizeit, a report was published about the MOIN CC-PLUS team and the 3D head model developed for sectional image simulations in MRI. From the RTG 2154, Eva Peschke and Frowin Ellermann (PI: Jan-Bernd Hövener) are part of the five-member MOIN CC-PLUS team. Since the UKSH Healthcare Hackathon in June 2020, the team has further developed its prototype, and is preparing for the Hackathon finals in January 2021 in Berlin, where it will compete against teams from the Charité Berlin and the University Medicine in Mainz.
    Unizeit article MOIN CC-PLUS
     

  • 19. - 20.10.2020: RTG 2154 Retreat in Sankelmark
    Under hygiene measures the 8th RTG 2154 Retreat could take place in Sankelmark. Most of the members were present, while others joined online. Besides presentations by the PhD students, in which they reported on their research projects, there were introductory lectures by PI's on their research area. In the evening, Prof. Su Ryon Shin from Harvard Medical School, Cambridge (USA), joined the Retreat by video and gave a talk entitled "Micro/Nano engineered biomaterials for manufacturing biomimetic tissues and biomedical applications".
    Retreat Oct 2020
     
  • 24.08.2020: Press release on RTG research work on glioblastoma treatment
    The successful research work of the projects P3, P7 and P8 to improve the treatment of glioblastomas was published in a press release of the CAU, the platform "Informationsdienst Wissenschaft" (Link), and was also sent to media nationwide. Vivian Adamski, Christina Schmitt and Florian Rasch present their approach using a special microstructured silicone matrix, enabling a more tailored drug release in the brain over a long period of time, and allowing a more gentle and efficient treatment.
    CAU full article: English and German
    Foto FLCE, CS, VA
    Florian, Rasch, Christina Schmitt, Vivian Adamski (© private)
     
  • 05.06.2020: RTG 2154 teams at the UKSH Healthcare Hackathon, Kiel
    The teams VesselGoGo, with Mariya Pravdivtseva, and MOIN CC-PLUS, with Frowin Ellermann and Eva Peschke, competed with 24 other teams in the UKSH Healthcare Hackathon, which was hosted for the first time virtually.
    VesselGoGo pursued the goal of developing a platform for training in endovascular treatment. This platform should enable physicians to practice interventions such as inserting a stent into patient-specific vascular models. You can see the VesselGoGo-presentation under Video.
    The MOINCC-PLUS team developed a device enabling an intuitive understanding of abstract radiological data. They developed a head model with the 3D printer and equipped it with a microcontroller. Using modern nanomechanical sensors and Bluetooth, the head signals its orientation in space with a PC. “By turning the head, the associated MRI or CT images also rotate. Depending on the direction of view, you can see the corresponding images and thus get intuitive access to radiological data,” explains Prof. Dr. Jan-Bernd Hövener, director at MOIN CC. This is helpful, for example, for patient education and medical teaching. You can see the MOIN CC-PLUS team in action under Video.
    The MOIN CC-PLUS team convinced the jury of experts: They are one of seven teams from the UKSH Healthcare Hackathon which will compete in January 2021 in the grand finale, the Health Innovation Hub in Berlin. Congratulations and good luck in Berlin!
    More info under Link
    VesselGoGo_MOIN CC Plus
     
  • 13. - 15.05.2020: RTG 2154 Online Retreat
    Due to the corona crisis, the Retreat of the RTG 2154 took place as an online-meeting. Positive effect of the online meeting: More than 50 members and guests over Germany, Europe and the world were able to participate in the event!
     
  • 21.04.2020: Kick-off-meeting for the 2nd PhD-generation of the RTG 2154
    The RTG 2154 is also impacted by the corona crisis. The kick-off-meeting for the 2nd PhD-generation, starting on 01. April 2020, had to take place online. Rainer Adelung, the new spokesperson of the RTG 2154, as well as PIs and the scientific coordinator welcomed the new students who participated via video-meeting. He gave an online-presentation on the structure and training program of the RTG 2154 and answered questions from the students. The students also gave a brief update on what they can and cannot do in these - for everyone - unusual times. At the end of the meeting a group photo was taken, saying hello to all the RTG-members! We hope to meet everyone in person soon!
    2020_group photo
     
  • 08.04.2020: RTG 2154 research on the cover page of ACS Biomaterials Science & Engineering
    The recent collaborative work within the RTG 2154 (Link) has been illustrated on the cover page of the journal ACS Biomaterials Science & Engineering. In this interdisciplinary study, the projects P3, P7, and P8 worked closely together and developed a microstructured silicone foam which could release a chemotherapeutic drug for several days. The results demonstrated its potential use as a drug delivery implant for the local treatment of the highly malignant brain tumor Glioblastoma multiforme.
    Cover ACS Biomaterials
     
  • 04.04.2020: News article about Mariya Pravdivtseva and Prasanth Velvaluri on aneurysm treatment
    Two of our PhD-students, Mariya Pravdivtseva and Prasanth Velvaluri, had the opportunity to present their research to the greater public in an Unizeit article of the CAU. Mariya, working with 3D-models and measuring blood-flow with MRI, and Prasanth, investigating new stent designs, are working as a tandem team. During their PhD, they constantly exchange their results and research progress in order to develop new stent designs, adapt the design if necessary and thus improve the treatment of brain aneurysms.
    Full article English and  German
    Unizeit news
    copyright: J. Siekmann
     
  • 01.04.2020: Start of the 2nd PhD-generation of the RTG 2154
    After succesfull three years of the 1st PhD-generation, the 2nd generation started on 01. April 2020. Twelve students will continue and progress the research in the different projects within Materials for Brain. The RTG 2154  investigates nano- and microscale therapeutically active coatings for their suitability as implants to treat three selected diseases of the brain (epilepsy, aneurysm, glioblastoma). Investigations according to material-controlled drug release, implant interactions as well as suitability of the implants for diagnostics with magnetic resonance imaging (MRI) are in the main focus of the research projects which can open up new prospects for novel therapies. The investigation and development of such cutting-edge localized therapies and suitable functional materials requires substantial interdisciplinary collaboration between materials science and medicine, and is characteristic for this Research Training Group.
    A warm welcome to our new RTG-students!
     
  • 14.01.2020: Approval of additional project in the RTG 2154
    The DFG approved an additional research project in the RTG 2154! Prof.-Ing. Stephan Wulfinghoff, head of the working group "Computational Materials Science", will be the Principal Investigator of project P12 "Chemo-mechanical continuum modeling of biocompatible degradation processes in thin-film implant materials". Congratulations!
    With this new project, starting at 01. April 2020, the RTG 2154 now includes a total of 14 research projects.