Research Training Group 2154 - Materials for Brain

  • 24.08.2020: Press release on RTG research work on glioblastoma treatment

The successful research work of the projects P3, P7 and P8 to improve the treatment of glioblastomas was published in a press release of the CAU, the platform "Informationsdienst Wissenschaft" (Link), and was also sent to media nationwide. Vivian Adamski, Christina Schmitt and Florian Rasch present their approach using a special microstructured silicone matrix, enabling a more tailored drug release in the brain over a long period of time, and allowing a more gentle and efficient treatment.
CAU full article: English and German
Florian, Rasch, Christina Schmitt, Vivian Adamski (© private)

  • 05.06.2020: RTG 2154 teams at the UKSH Healthcare Hackathon, Kiel

The teams VesselGoGo, with Mariya Pravdivtseva, and MOIN CC-PLUS, with Frowin Ellermann and Eva Peschke, competed with 24 other teams in the UKSH Healthcare Hackathon, which was hosted for the first time virtually.
VesselGoGo pursued the goal of developing a platform for training in endovascular treatment. This platform should enable physicians to practice interventions such as inserting a stent into patient-specific vascular models. You can see the VesselGoGo-presentation under Video.
The MOINCC-PLUS team developed a device enabling an intuitive understanding of abstract radiological data. They created a head with the 3D printer and equipped it with a microcontroller. Using modern nanomechanical sensors and Bluetooth, the head shares its orientation in space with a PC. “By turning the head, the associated MRI or CT images also rotate. Depending on the direction of view, you can see the corresponding images and thus get intuitive access to radiological data,” explains Prof. Dr. Jan-Bernd Hövener, director at MOIN CC. This is helpful, for example, for patient education and medical teaching. You can see the MOIN CC-PLUS team in action under Video.
The MOIN CC-PLUS team convinced the jury of experts: They are one of seven teams from the UKSH Healthcare Hackathon which will compete in January 2021 in the grand finale, the Health Innovation Hub in Berlin. Congratulations and good luck in Berlin!
More info under Link

VesselGoGo_MOIN CC Plus

  • 13. - 15.05.2020: RTG 2154 Online Retreat

Due to the corona crisis, the Retreat of the RTG 2154 took place as an online-meeting. Positive effect of the online meeting: More than 50 members and guests over Germany, Europe and the world were able to participate in the event!

  • 21.04.2020: Kick-off-meeting for the 2nd PhD-generation of the RTG 2154

The RTG 2154 is also impacted by the corona crisis. The kick-off-meeting for the 2nd PhD-generation, starting on 01. April 2020, had to take place online. Rainer Adelung, the new spokesperson of the RTG 2154, as well as PIs and the scientific coordinator welcomed the new students who participated via video-meeting. He gave an online-presentation on the structure and training program of the RTG 2154 and answered questions from the students. The students also gave a brief update on what they can and cannot do in these - for everyone - unusual times. At the end of the meeting a group photo was taken, saying hello to all the RTG-members! We hope to meet everyone in person soon!

2020_group photo

  • 08.04.2020: RTG 2154 research on the cover page of ACS Biomaterials Science & Engineering

The recent collaborative work within the RTG 2154 (Link) has been illustrated on the cover page of the journal ACS Biomaterials Science & Engineering. In this interdisciplinary study, the projects P3, P7, and P8 worked closely together and developed a microstructured silicone foam which could release a chemotherapeutic drug for several days. The results demonstrated its potential use as a drug delivery implant for the local treatment of the highly malignant brain tumor Glioblastoma multiforme.

Cover ACS Biomaterials

  • 04.04.2020: News article about Mariya Pravdivtseva and Prasanth Velvaluri on aneurysm treatment

Two of our PhD-students, Mariya Pravdivtseva and Prasanth Velvaluri, had the opportunity to present their research to the greater public in an Unizeit article of the CAU. Mariya, working with 3D-models and measuring blood-flow with MRI, and Prasanth, investigating new stent designs, are working as a tandem team. During their PhD, they constantly exchange their results and research progress in order to develop new stent designs, adapt the design if necessary and thus improve the treatment of brain aneurysms.
Full article English and  German

Unizeit news
copyright: J. Siekmann

  • 01.04.2020: Start of the 2nd PhD-generation of the RTG 2154

After succesfull three years of the 1st PhD-generation, the 2nd generation started on 01. April 2020. Twelve students will continue and progress the research in the different projects within Materials for Brain. The RTG 2154  investigates nano- and microscale therapeutically active coatings for their suitability as implants to treat three selected
diseases of the brain (epilepsy, aneurysm, glioblastoma). Investigations according to material-controlled drug release, implant interactions as well as suitability of the implants for diagnostics with magnetic resonance imaging (MRI) are in the main focus of the research projects which can open up new prospects for novel therapies. The investigation and development of such cutting-edge localized therapies and suitable functional materials requires substantial interdisciplinary collaboration between materials science and medicine, and is characteristic for this Research Training Group.
A warm welcome to our new RTG-students!

  • 14.01.2020: Approval of additional project in the RTG 2154

The DFG approved an additional research project in the RTG 2154! Prof.-Ing. Stephan Wulfinghoff, head of the working group "Computational Materials Science", will be the Principal Investigator of project P12 "Chemo-mechanical continuum modeling of biocompatible degradation processes in thin-film implant materials". Congratulations!
With this new project, starting at 01. April 2020, the RTG 2154 now includes a total of 14 research projects.