Research Training Group 2154 - Materials for Brain

RTG Online Colloquium talk by (1) Dr. Berit Zeller-Plumhoff: Multiscale characterisation of biological and materials systems, and (2) Dr. Andrey Pravdivtsev: Physics of para-hydrogen induced polarization and magnetic resonance imaging

(1) Institute of Materials Research, Division of Metallic Biomaterials, Biological Characterisation, Helmholtz-Zentrum Geesthacht (2) Clinic for Radiology and Neuroradiology, UKSH, Molecular Imaging North Competence Center (MOIN CC), Section Biomedical Imaging, Kiel University

Jun 18, 2020 from 05:00 PM to 06:00 PM

Online

Please use the following link for the video-meeting:
Link to the Video-Meeting

Dr. Berit Zeller-Plumhoff:
Synchrotron radiation-based computed tomography (SR CT) is a powerful tool for non-destructive three-dimensional imaging of materials both on the micro- and the nanoscale. During this talk, I will showcase applications from materials science and biology, where SR CT has been used successfully to determine the morphology of the given material. Examples will include the static analysis of magnesium alloy precipitate evolution after plastic deformation, in situ imaging of magnesium degradation and in situ compression testing of ZnO tetrapodal networks. In combination with image-based mathematical modelling, SR CT further enables the correlation between morphological and/or structural material measures and their function, as I will show with an example of mouse muscle oxygenation. Finally, the application of complementary techniques based on synchrotron radiation, such as X-ray diffraction and small angle X-ray scattering, will be referred to for the anal-ysis of the bone ultrastructure around biodegradable magnesium implants.

 

Dr. Andrey Pravdivtsev:
Magnetic resonance (MR) is one of the most versatile physical effects used for human imaging, chemical analysis, and the elucidation of molecular structures. However, its full potential is rarely used, because only a small fraction of the nuclear spin ensemble contributes to the MR signal. This fraction is polarized, that is, aligned with the applied static magnetic field. As a result, the effective signal to noise ratio (SNR), which is the limiting factor in many applications, can be increased manifold. I’m addressing this challenge in my work and talk from two sides: reducing unwanted signals and increasing the desired signals using spin hyperpolarization and long-lived spin states.

 

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