Research Training Group 2154 - Materials for Brain

Project 1a: Lisa Hanke (Student Representative)

Magnesium is widely discussed as a material for the production of biodegradable and, thus, temporary neuro-implants. Alloying elements can further tailor the material properties and therapeutically active alloying ions can additionally serve as medical treatment during the degradation of the implant.
In this project, the results and developed techniques of the first PhD generation, which dealt with Magnesium-Silver (MgAg) alloys, will be used to study further Mg alloys, e.g., Magnesium-Lithium (MgLi). Alloying with the correct amount of lithium not only can be beneficial for material properties but can also have a medical impact since lithium is used as a treatment of mood disorders.
Freestanding magnesium alloy thin films with a thickness of around 20 µm are fabricated using magnetron sputtering and UV-lithography techniques. Mechanical and corrosion properties are tested and, additionally, the microstructure and crystallographic properties are studied using SEM, XRD and TEM. Furthermore, ternary alloy films (e.g. MgAgLi) can be produced to combine positive effects for material parameters and therapeutic activity.
Testing of the corrosion properties of the films in brain-like conditions and the interaction of brain cells with the films will be carried out in P1b (Krathika Bhat).

Lisa Hanke